The Basic Science Program (BSP) pursues independent, multidisciplinary research in basic and applied molecular biology, immunology, retrovirology, cancer biology, and human genetics. Research efforts and support are an integral part of the Center for Cancer Research (CCR) at the Frederick National Laboratory for Cancer Research (FNLCR).
In support of the research efforts of Dr. James Kochenderfer, and the Center for Cancer Research, Experimental Transplantation amp; Immunology Branch, whose research efforts are focused on chimeric antigen receptor T-cell therapies. Chimeric antigen receptors (CARs) are fusion proteins that recognize malignant cells. T cells genetically engineered to express CARs can be infused into patients to treat cancer. Dr. Kochenderfer leads laboratory studies of CAR T-cell biology and clinical studies of CAR T-cell therapies for multiple myeloma and for treatment of B-cell malignancies after allogeneic hematopoietic stem cell transplantation. The BSP requires a technician to support these research efforts.
The Research Technician will be responsible for:
- Performance of cell culture
- RNA amp; DNA extractions
- Performance of qPCR, ELISA assays, and flow cytometry
- Active participation in animal experiments, to include intravenous injections (either retro-bulbar or tail vein), intraperitoneal injections, subcutaneous injections
- Basic mouse handling skills
- Establishment and maintenance of lab records
- Ordering of laboratory supplies
To be considered for this position, you must minimally meet the knowledge, skills, and abilities listed below:
- Possession of a Bachelor rsquo;s degree from an accredited college/university according to the Council for Higher Education Accreditation (CHEA) in a field related to biomedical research. Foreign degrees must be evaluated for US equivalency. (Additional qualifying experience may be substituted for the required education).
- No experience is required with a Bachelor rsquo;s degree
- Must be able to obtain and maintain a security clearance
Candidates with these desired skills will be given preferential consideration:
- Previous mouse handling experience, and experience participating in mouse experiments, as outlined in the job responsibilities
- Knowledge and experience with aseptic technique
- Knowledge and experience in the performance of qPCR, ELISA, flow cytometry
- Experience maintaining lab records and ordering lab supplies
- Ability to work alone and in a team environment
- Routine problem solving abilities
- Basic understanding of general laboratory skills
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